Inhibiting locus coeruleus input to the medial prefrontal cortex in mice impaired task performance, affected the tuning of single cortical neurons and disrupted population dynamics and encoding ...

When facing new situations or problems, humans typically rely on knowledge they acquired in the past. Specifically, ...

Neuronal sequences in the medial prefrontal cortex of the brain encode critical information associated with a procedural rule. These sequences can be explored and leveraged as novel biomarkers for ...

Whether people are mulling over the pros and cons of a purchase or assessing their interactions with new people, they may ...

In a stylized regime-shift detection task, human fMRI evidence shows that under- and overreactions to change arise from dissociable contributions of the frontoparietal network and ventromedial ...

Many horse owners think the existence of the prefrontal cortex is a major controversy in equine science. It’s not. It’s just an area that’s riddled with misinformation. Curiously, most people—horsey ...

For more than a decade, neuroscientists had recordings from monkey brains learning to sort visual patterns. They had analyzed ...

To understand our brains, there is no insight more fundamental than this: The mind is modular (LeDoux, 2003). This means the brain is not one single, unitary entity but an amalgamation of different ...

When a writer comes up with a striking metaphor, when an engineer solves a tricky problem by combining seemingly unrelated tools, or when a child invents the rules of a new game, what happens in the ...